4QO9
MST3 IN COMPLEX WITH Danusertib
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | SERINE/THREONINE-PROTEIN KINASE 24 | polymer | 310 | 35023.9 | 2 | UniProt (Q9Y6E0) Pfam (PF00069) In PDB | Homo sapiens (human) | STE20-LIKE KINASE MST3, MST-3, MAMMALIAN STE20-LIKE PROTEIN KINASE 3 |
2 | A, B | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
5 | A, B | N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE | non-polymer | 474.6 | 2 | Chemie (627) | |||
6 | B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
7 | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 303 (UniProt: Q9Y6E0)
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Pro -5 | - | expression tag |
Leu -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Glu -1 | - | expression tag |
Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 70047.9 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1487.2 | |
All* | Total formula weight | 71535.0 |