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4QO8

Lactate Dehydrogenase A in complex with substituted 3-Hydroxy-2-mercaptocyclohex-2-enone compound 104

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
L-lactate dehydrogenase A chainpolymer33136603.54UniProt (P00338)
Pfam (PF00056)
Pfam (PF02866)
Homo sapiens (human)LDH-A, Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59
2E, I, M, Q
(A, B, C, D)
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDEnon-polymer665.44Chemie (NAI)
3F, J, N
(A, B, C)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.33Chemie (EPE)
4G, L, O, R
(A, B, C, D)
SULFATE IONnon-polymer96.14Chemie (SO4)
5H, P, S
(A, C, D)
(5S)-2-[(2-chlorophenyl)sulfanyl]-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-onenon-polymer399.73Chemie (36U)
6K
(B)
LACTIC ACIDnon-polymer90.11Chemie (LAC)
7T, U, V, W
(A, B, C, D)
waterwater18.0773Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight146413.9
Non-Polymers*Number of molecules15
Total formula weight5050.2
All*Total formula weight151464.1
*Water molecules are not included.

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PDB entries from 2026-01-28

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