4QNZ
Crystal structure of rhomboid intramembrane protease GlpG F146I in complex with peptide derived inhibitor Ac-FATA-cmk
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Rhomboid protease GlpG | polymer | 200 | 22703.9 | 1 | UniProt (U6NA71) | Escherichia coli | Intramembrane serine protease |
| 2 | B (B) | ACE-PHE-ALA-THR-ALA-0QE | polymer | 6 | 467.0 | 1 | BIRD (PRD_001251) | ||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | nonyl beta-D-glucopyranoside | non-polymer | 306.4 | 1 | Chemie (BNG) | |||
| 5 | E (A) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A: 87 - 276 (UniProt: U6NA71)
| PDB | External Database | Details |
|---|---|---|
| Ile 146 | Phe 146 | engineered mutation |
| Ala 277 | - | expression tag |
| Ser 278 | - | expression tag |
| Leu 279 | - | expression tag |
| Glu 280 | - | expression tag |
| Arg 281 | - | expression tag |
| Glu 282 | - | expression tag |
| Asn 283 | - | expression tag |
| Leu 284 | - | expression tag |
| Tyr 285 | - | expression tag |
| Phe 286 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23170.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 341.8 | |
| All* | Total formula weight | 23512.7 |
