4QNE

Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with NAD and IMP

Replaces:  4HLV

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Inosine 5'-monophosphate dehydrogenase	polymer	366	38247.7	2	UniProt (Q9KTW3) Pfam (PF00478)	Vibrio cholerae O1 biovar El Tor
2	C, F (A, B)	INOSINIC ACID	non-polymer		348.2	2	Chemie (IMP) PubChem (177678963) PubChem (135464200) PubChem (135533971) PubChem (138454308) PubChem (135398640) PubChem (135402036) PubChem (135449337) PubChem (135486133) PubChem (135530792) PubChem (135567013) PubChem (135705234) PubChem (135854804) PubChem (135889742) PubChem (136026456) PubChem (136073920) PubChem (136217866) PubChem (136259539) PubChem (136716177) PubChem (136766861) PubChem (136811071) PubChem (137162990) PubChem (137168789) PubChem (137257909) PubChem (162510533) PubChem (174152734)
3	D, G (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM)	non-polymer		663.4	2	Chemie (NAJ)
4	E, H (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K) PubChem (813)
5	I, J (A, B)	water	water		18.0	178	Chemie (HOH)

Sequence modifications

A, B: 1 - 90 (UniProt: Q9KTW3)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

A, B: 220 - 489 (UniProt: Q9KTW3)

PDB	External Database	Details
Ser 91	-	linker
Gly 92	-	linker
Gly 93	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76495.4
Non-Polymers*	Number of molecules	6
	Total formula weight	2101.5
All*	Total formula weight	78596.9

*Water molecules are not included.