4QNB
Disulfide stabilized HIV-1 CA hexamer in complex with PHENYL-L-PHENYLALANINAMIDE inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CAPSID PROTEIN P24 | polymer | 231 | 25461.3 | 1 | UniProt (P12497) Pfam (PF19317) | Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) (HIV-1) | |
| 2 | B (A) | N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE | non-polymer | 425.5 | 1 | Chemie (1B0) | |||
| 3 | C (A) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P12497)
| PDB | External Database | Details |
|---|---|---|
| Cys 14 | Ala 146 | engineered mutation |
| Cys 45 | Glu 177 | engineered mutation |
| Ala 184 | Trp 316 | engineered mutation |
| Ala 185 | Met 317 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25461.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 425.5 | |
| All* | Total formula weight | 25886.8 |
