4QMU
MST3 IN COMPLEX WITH JNJ-7706621, 4-({5-AMINO-1-[(2,6-DIFLUOROPHENYL)CARBONYL]-1H-1,2,4-TRIAZOL-3-YL}AMINO)BENZENESULFONAMIDE
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | SERINE/THREONINE-PROTEIN KINASE 24 | polymer | 310 | 35023.9 | 1 | UniProt (Q9Y6E0) Pfam (PF00069) In PDB | Homo sapiens (human) | STE20-LIKE KINASE MST3, MST-3, MAMMALIAN STE20-LIKE PROTEIN KINASE 3 |
2 | A | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide | non-polymer | 394.4 | 1 | Chemie (SKE) | |||
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
5 | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence modifications
A: 1 - 303 (UniProt: Q9Y6E0)
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Pro -5 | - | expression tag |
Leu -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Glu -1 | - | expression tag |
Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35023.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 496.8 | |
All* | Total formula weight | 35520.7 |