4QMS
MST3 in complex with DASATINIB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase 24 | polymer | 310 | 35023.9 | 1 | UniProt (Q9Y6E0) Pfam (PF00069) In PDB | Homo sapiens (human) | Mammalian STE20-like protein kinase 3, MST-3, STE20-like kinase MST3, Serine/threonine-protein kinase 24 36 kDa subunit, Mammalian STE20-like protein kinase 3 N-terminal, MST3/N, Serine/threonine-protein kinase 24 12 kDa subunit, Mammalian STE20-like protein kinase 3 C-terminal, MST3/C |
| 2 | A | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE | non-polymer | 488.0 | 1 | Chemie (1N1) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A: 1 - 303 (UniProt: Q9Y6E0)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35023.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 585.5 | |
| All* | Total formula weight | 35609.5 |
