4QKZ
X-ray structure of the catalytic domain of MMP-8 with the inhibitor ML115
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neutrophil collagenase | polymer | 163 | 18111.7 | 1 | UniProt (P22894) Pfam (PF00413) | Homo sapiens (human) | Matrix metalloproteinase-8, MMP-8, PMNL collagenase, PMNL-CL |
| 2 | B, C (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | D, E (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | F (A) | {[(biphenyl-4-ylsulfonyl)amino]methanediyl}bis(phosphonic acid) | non-polymer | 407.3 | 1 | Chemie (QZK) | |||
| 5 | G (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 6 | H (A) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18111.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 813.5 | |
| All* | Total formula weight | 18925.2 |
