4QIY
Crystal structure of human carbonic anhydrase isozyme II with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Carbonic anhydrase 2 | polymer | 260 | 29289.1 | 4 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (human) | Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II |
| 2 | E, I, M, Q (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, J, N, R (A, B, C, D) | 2,3,6-trifluoro-5-{[(1R,2S)-2-hydroxy-1,2-diphenylethyl]amino}-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide | non-polymer | 530.5 | 4 | Chemie (WWX) | |||
| 4 | G, K, O, S (A, B, C, D) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 5 | H, L, P, T (A, B, C, D) | BICINE | non-polymer | 163.2 | 4 | Chemie (BCN) | |||
| 6 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 1013 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 117156.2 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3349.0 | |
| All* | Total formula weight | 120505.3 |
