4QII

Crystal Structure of type II MenB from Mycobacteria tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	1,4-Dihydroxy-2-naphthoyl-CoA synthase	polymer	334	36903.3	12	UniProt (P9WNP5) Pfam (PF00378)	Mycobacterium tuberculosis H37Rv	DHNA-CoA synthase
2	AA, BA, M, N, P... (K, L, A, B, C...)	Salicylyl CoA	non-polymer		887.6	12	Chemie (2NE)
3	O, R, V, Z (B, D, G, J)	TRIETHYLENE GLYCOL	non-polymer		150.2	4	Chemie (PGE)
4	CA, DA, EA, FA, GA... (A, B, C, D, E...)	water	water		18.0	3856	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 1 - 314 (UniProt: P9WNP5)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	442839.6
Non-Polymers*	Number of molecules	16
	Total formula weight	11252.4
All*	Total formula weight	454092.0

*Water molecules are not included.