4QHD
Crystal structure of apo human APE1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA-(apurinic or apyrimidinic site) lyase | polymer | 285 | 32011.4 | 1 | UniProt (P27695) Pfam (PF03372) In PDB | Homo sapiens (human) | APEX nuclease, APEN, Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1, APE-1, REF-1, Redox factor-1, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial |
| 2 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 3 | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A: 38 - 318 (UniProt: P27695)
| PDB | External Database | Details |
|---|---|---|
| Gly 34 | - | expression tag |
| Ser 35 | - | expression tag |
| His 36 | - | expression tag |
| Met 37 | - | expression tag |
| Ser 39 | Gly 39 | variant |
| Ala 138 | Cys 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32011.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 248.3 | |
| All* | Total formula weight | 32259.6 |
