4QG7
S.aureus TMK in complex with a potent inhibitor compound 18, 2-(3-CHLOROPHENOXY)-3-METHOXY-4-{[(3S)-3-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)PIPERIDIN-1-YL]METHYL}BENZOIC ACID
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thymidylate kinase | polymer | 205 | 23454.6 | 2 | UniProt (Q6GJI9) Pfam (PF02223) | Staphylococcus aureus subsp. aureus | dTMP kinase |
| 2 | C, D (A, B) | 2-(3-chlorophenoxy)-3-methoxy-4-{[(3S)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)piperidin-1-yl]methyl}benzoic acid | non-polymer | 499.9 | 2 | Chemie (32K) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 236 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46909.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 999.9 | |
| All* | Total formula weight | 47909.1 |
