4QDH

Crystal Structure of the C-terminal Domain of Mouse TLR9

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Variable lymphocyte receptor B, Toll-like receptor 9 chimera	polymer	438	48774.5	2	UniProt (Q4G1L2) UniProt (Q9EQU3) Pfam (PF13855) Pfam (PF11921) In PDB	Eptatretus burgeri (Inshore hagfish mouse)	Innate Immune Receptor
2	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)
3	A, B	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
4		water	water		18.0	120	Chemie (HOH)

Sequence modifications

A, B: -2 - 58 (UniProt: Q4G1L2)

PDB	External Database	Details
Ala -6	-	expression tag
Asp -5	-	expression tag
Pro -4	-	expression tag
Gly -3	-	expression tag

A, B: 59 - 332 (UniProt: Q9EQU3)
A, B: 333 - 407 (UniProt: Q4G1L2)

PDB	External Database	Details
Ala 408	-	expression tag
Ser 409	-	expression tag
Leu 410	-	expression tag
Val 411	-	expression tag
Pro 412	-	expression tag
Arg 413	-	expression tag
Gly 414	-	expression tag
Ser 415	-	expression tag
Trp 416	-	expression tag
Ser 417	-	expression tag
His 418	-	expression tag
Pro 419	-	expression tag
Gln 420	-	expression tag
Phe 421	-	expression tag
Glu 422	-	expression tag
Lys 423	-	expression tag
Gly 424	-	expression tag
Ser 425	-	expression tag
His 426	-	expression tag
His 427	-	expression tag
His 428	-	expression tag
His 429	-	expression tag
His 430	-	expression tag
His 431	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	97549.1
Non-Polymers*	Number of molecules	18
	Total formula weight	2980.6
All*	Total formula weight	100529.7

*Water molecules are not included.