4Q6E
Crystal structure of human carbonic anhydrase isozyme II with 4-{[3-(3,5-Dimethyl-1H-pyrazol-1-yl)-3-oxopropyl]amino}benzene-1-sulfonamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Carbonic anhydrase 2 | polymer | 260 | 29289.1 | 1 | UniProt (P00918) Pfam (PF00194) In PDB | Homo sapiens (human) | Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | BICINE | non-polymer | 163.2 | 1 | Chemie (BCN) | |||
4 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
5 | A | 4-{[3-(3,5-dimethyl-1H-pyrazol-1-yl)-3-oxopropyl]amino}benzenesulfonamide | non-polymer | 322.4 | 1 | Chemie (KR5) | |||
6 | water | water | 18.0 | 321 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29289.1 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 707.2 | |
All* | Total formula weight | 29996.3 |