4Q32

Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and C91

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Inosine-5'-monophosphate dehydrogenase	polymer	363	38441.3	4	UniProt (Q0TN42) Pfam (PF00478) UniProt (by SIFTS) (A0A0H2YRZ7)	Clostridium perfringens	IMP dehydrogenase, IMPD, IMPDH
2	E, H, J, L (A, B, C, D)	INOSINIC ACID	non-polymer		348.2	4	Chemie (IMP)
3	F, G, I, K (A, B, D)	N-(naphthalen-2-yl)-2-[2-(pyridin-2-yl)-1H-benzimidazol-1-yl]acetamide	non-polymer		378.4	4	Chemie (C91)
4	M, N, O, P (A, B, C, D)	water	water		18.0	81	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 88 (UniProt: Q0TN42)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

A, B, C, D: 92 - 360 (UniProt: Q0TN42)

PDB	External Database	Details
Ser 89	-	linker
Gly 90	-	linker
Gly 91	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	153765.1
Non-Polymers*	Number of molecules	8
	Total formula weight	2906.5
All*	Total formula weight	156671.6

*Water molecules are not included.