4Q2P
NHERF3 PDZ2 in Complex with a Phage-Derived Peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Na(+)/H(+) exchange regulatory cofactor NHE-RF3 | polymer | 99 | 10699.3 | 3 | UniProt (Q5T2W1) Pfam (PF00595) | Homo sapiens (human) | NHERF-3, CFTR-associated protein of 70 kDa, Na(+)/H(+) exchanger regulatory factor 3, Na/Pi cotransporter C-terminal-associated protein 1, NaPi-Cap1, PDZ domain-containing protein 1, Sodium-hydrogen exchanger regulatory factor 3 |
| 2 | D (B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 3 | E (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | F, G, H (A, B, C) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A, B, C: 132 - 215 (UniProt: Q5T2W1)
| PDB | External Database | Details |
|---|---|---|
| Gly 128 | - | expression tag |
| Ser 129 | - | expression tag |
| His 130 | - | expression tag |
| Met 131 | - | expression tag |
| Ala 216 | - | linker |
| Ala 217 | - | linker |
| Gly 218 | - | linker |
| Gly 219 | - | linker |
| Gly 220 | - | linker |
| Ile 221 | - | SEE REMARK 999 |
| Lys 222 | - | SEE REMARK 999 |
| Ile 223 | - | SEE REMARK 999 |
| Thr 224 | - | SEE REMARK 999 |
| Lys 225 | - | SEE REMARK 999 |
| Phe 226 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 32097.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 32282.1 |
