4PZS
Crystal structure of p300 histone acetyltransferase domain in complex with Acetyl-Coenzyme A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histone acetyltransferase p300 | polymer | 378 | 43701.7 | 1 | UniProt (Q09472) Pfam (PF08214) In PDB | Homo sapiens (human) | p300 HAT, E1A-associated protein p300 |
| 2 | A | ACETYL COENZYME *A | non-polymer | 809.6 | 1 | Chemie (ACO) | |||
| 3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | water | water | 18.0 | 251 | Chemie (HOH) |
Sequence modifications
A: 1287 - 1664 (UniProt: Q09472)
| PDB | External Database | Details |
|---|---|---|
| Phe 1467 | Tyr 1467 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43701.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 887.7 | |
| All* | Total formula weight | 44589.4 |
