4PZ1

Crystal structure of a sHIP (UniProt Id: Q99XU0) mutant from Streptococcus pyogenes

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	sHIP	polymer	98	11350.7	1	UniProt (Q99XU0) Pfam (PF14131) In PDB	Streptococcus pyogenes serotype M1
2	A	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
3	A	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
4		water	water		18.0	78	Chemie (HOH)

Sequence modifications

A: 3 - 98 (UniProt: Q99XU0)

PDB	External Database	Details
Ser 1	-	expression tag
Met 2	-	expression tag
Ser 65	Cys 65	engineered mutation
Ala 84	Leu 84	engineered mutation
Ala 88	Leu 88	engineered mutation
Ala 95	Tyr 95	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	11350.7
Non-Polymers*	Number of molecules	3
	Total formula weight	111.0
All*	Total formula weight	11461.7

*Water molecules are not included.