4PYN
Humanized rat COMT in complex with SAH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Catechol O-methyltransferase | polymer | 221 | 24694.3 | 1 | UniProt (P22734) Pfam (PF01596) | Rattus norvegicus (rat) | |
| 2 | B (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (118560068) PubChem (126969526) PubChem (189149) PubChem (13792) PubChem (163054214) PubChem (439155) PubChem (118374891) PubChem (5284331) PubChem (6419189) PubChem (129105892) PubChem (13231890) PubChem (16760024) PubChem (21125603) PubChem (143518505) PubChem (154578335) PubChem (25203782) PubChem (25210495) PubChem (44361184) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (163335525) PubChem (164157219) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70832431) PubChem (71170554) PubChem (193) PubChem (52224400) PubChem (57544532) PubChem (59046843) PubChem (70702054) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 4 | D, E, F (A) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) PubChem (813) | |||
| 5 | G (A) | water | water | 18.0 | 314 | Chemie (HOH) |
Sequence modifications
A: 44 - 264 (UniProt: P22734)
| PDB | External Database | Details |
|---|---|---|
| Ile 134 | Met 134 | engineered mutation |
| Cys 138 | Tyr 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24694.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 537.2 | |
| All* | Total formula weight | 25231.5 |
