4PXW

Crystal structure of human DCAF1 WD40 repeats (Q1250L)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein VPRBP	polymer	381	43636.9	2	UniProt (Q9Y4B6)	Homo sapiens (human)	DDB1- and CUL4-associated factor 1, HIV-1 Vpr-binding protein, VprBP, Serine/threonine-protein kinase VPRBP, Vpr-interacting protein
2	AA, BA, C, CA, D... (B, A)	UNKNOWN ATOM OR ION	non-polymer			45	Chemie (UNX)
3	VA, WA (A, B)	water	water		18.0	413	Chemie (HOH)

Sequence modifications

A, B: 1039 - 1401 (UniProt: Q9Y4B6)

PDB	External Database	Details
Met 1021	-	initiating methionine
His 1022	-	expression tag
His 1023	-	expression tag
His 1024	-	expression tag
His 1025	-	expression tag
His 1026	-	expression tag
His 1027	-	expression tag
Ser 1028	-	expression tag
Ser 1029	-	expression tag
Gly 1030	-	expression tag
Arg 1031	-	expression tag
Glu 1032	-	expression tag
Asn 1033	-	expression tag
Leu 1034	-	expression tag
Tyr 1035	-	expression tag
Phe 1036	-	expression tag
Gln 1037	-	expression tag
Gly 1038	-	expression tag
Leu 1250	Gln 1250	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	87273.7
Non-Polymers*	Number of molecules	45
	Total formula weight	0.0
All*	Total formula weight	87273.7

*Water molecules are not included.