4PVO
Crystal Structure of VIM-2 metallo-beta-lactamase in complex with ML302 and ML302F
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Beta-lactamase class B VIM-2 | polymer | 242 | 25693.5 | 2 | UniProt (Q9K2N0) Pfam (PF00753) In PDB | Pseudomonas aeruginosa | Class B beta-lactamase, Metallo beta-lactamase, Metallo-beta-lactamase, Metallo-beta-lactamase VIM-2, Mettalo-beta-lactamase VIM-2, VIM-2, VIM-2 class B metallo b-lactamase, VIM-2 protein, VIM-2 type metallo-beta-lactamase |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | A, B | (2Z)-2-sulfanyl-3-(2,3,6-trichlorophenyl)prop-2-enoic acid | non-polymer | 283.6 | 2 | Chemie (S3C) | |||
| 4 | A | N-(4-methylpiperazin-1-yl)-2-[(5Z)-4-oxo-2-thioxo-5-(2,3,6-trichlorobenzylidene)-1,3-thiazolidin-3-yl]acetamide | non-polymer | 479.8 | 1 | Chemie (SVB) | |||
| 5 | A, B | FORMIC ACID | non-polymer | 46.0 | 4 | Chemie (FMT) | |||
| 6 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 7 | water | water | 18.0 | 536 | Chemie (HOH) |
Sequence modifications
A, B: 25 - 300 (UniProt: Q9K2N0)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| Pro 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51387.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1701.6 | |
| All* | Total formula weight | 53088.6 |
