4PTF

Ternary crystal structure of yeast DNA polymerase epsilon with template G

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA polymerase epsilon catalytic subunit A	polymer	1194	137458.9	1	UniProt (P21951) Pfam (PF03104) Pfam (PF22634)	Saccharomyces cerevisiae (Baker's yeast)	DNA polymerase II subunit A
2	B (P)	5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3'	polymer	12	3502.3	1
3	C (T)	5'-D(*TP*AP*AP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3'	polymer	16	5067.3	1
4	D (A)	2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE	non-polymer		467.2	1	Chemie (DCP)
5	E, F, G, I (A, T)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
6	H (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
7	J (T)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
8	K, L, M (A, P, T)	water	water		18.0	147	Chemie (HOH)

Sequence modifications

A: 1 - 1187 (UniProt: P21951)

PDB	External Database	Details
Gly -6	-	expression tag
Pro -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Asp -2	-	expression tag
Pro -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	146028.5
Non-Polymers*	Number of molecules	7
	Total formula weight	712.5
All*	Total formula weight	146741.1

*Water molecules are not included.