4PSW

Crystal structure of histone acetyltransferase complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Histone acetyltransferase type B catalytic subunit	polymer	317	37277.0	1	UniProt (Q12341) Pfam (PF10394) Pfam (PF00583) Pfam (PF21184) In PDB	Saccharomyces cerevisiae (Baker's yeast)
2	B	Histone acetyltransferase type B subunit 2	polymer	401	45187.9	1	UniProt (P39984) Pfam (PF12265) Pfam (PF00400) In PDB	Saccharomyces cerevisiae (Baker's yeast)
3	C	Histone H4 type VIII	polymer	38	4134.0	1	UniProt (V8PGJ1) In PDB	Ophiophagus hannah (King cobra)
4	A	COENZYME A	non-polymer		767.5	1	Chemie (COA)
5		water	water		18.0	526	Chemie (HOH)

Sequence modifications

B: 7 - 390 (UniProt: P39984)

PDB	External Database	Details
Met 1	-	EXPRESSION TAG
Glu 2	-	EXPRESSION TAG
Asn 3	-	EXPRESSION TAG
Gln 4	-	EXPRESSION TAG
Glu 5	-	EXPRESSION TAG
Lys 6	-	EXPRESSION TAG
Thr 143	Val 143	ENGINEERED MUTATION
Gly 391	-	EXPRESSION TAG
Pro 392	-	EXPRESSION TAG
Pro 393	-	EXPRESSION TAG
Lys 394	-	EXPRESSION TAG
Val 395	-	EXPRESSION TAG
Asn 396	-	EXPRESSION TAG
Lys 397	-	EXPRESSION TAG
Asp 398	-	EXPRESSION TAG
Ile 399	-	EXPRESSION TAG
Ile 400	-	EXPRESSION TAG
Ser 401	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	86598.9
Non-Polymers*	Number of molecules	1
	Total formula weight	767.5
All*	Total formula weight	87366.4

*Water molecules are not included.