4POD
Structure of Triosephosphate Isomerase I170V mutant human enzyme.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Triosephosphate isomerase | polymer | 254 | 27212.0 | 2 | UniProt (P60174) Pfam (PF00121) | Homo sapiens (human) | TIM, Triose-phosphate isomerase |
| 2 | C, G (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 3 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | E (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | F (B) | BROMIDE ION | non-polymer | 79.9 | 1 | Chemie (BR) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 248 (UniProt: P60174)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Ile -3 | - | expression tag |
| Thr -2 | - | expression tag |
| His -1 | - | expression tag |
| Val 170 | Ile 208 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54424.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 276.1 | |
| All* | Total formula weight | 54700.0 |
