4PMN

Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in complex with MES (monoclinic crystal form I)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tat-secreted protein Rv2525c	polymer	234	25573.1	2	UniProt (P95028) Pfam (PF08924) In PDB	Mycobacterium tuberculosis
2	A, B	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
3	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	B	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5		water	water		18.0	420	Chemie (HOH)

Sequence modifications

A, B: 36 - 240 (UniProt: P95028)

PDB	External Database	Details
Mse 7	-	initiating methionine
Ser 8	-	expression tag
Tyr 9	-	expression tag
Tyr 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
Leu 17	-	expression tag
Glu 18	-	expression tag
Ser 19	-	expression tag
Thr 20	-	expression tag
Ser 21	-	expression tag
Leu 22	-	expression tag
Tyr 23	-	expression tag
Lys 24	-	expression tag
Lys 25	-	expression tag
Ala 26	-	expression tag
Gly 27	-	expression tag
Ser 28	-	expression tag
Glu 29	-	expression tag
Asn 30	-	expression tag
Leu 31	-	expression tag
Tyr 32	-	expression tag
Phe 33	-	expression tag
Gln 34	-	expression tag
Gly 35	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51146.3
Non-Polymers*	Number of molecules	4
	Total formula weight	578.6
All*	Total formula weight	51724.9

*Water molecules are not included.