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4PME

Human transthyretin (TTR) complexed with ferulic acid and curcumin.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Transthyretinpolymer11812961.62UniProt (P02766)
Pfam (PF00576)
Homo sapiens (Human)ATTR,Prealbumin,TBPA
2C
(A)
(1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-onenon-polymer368.41Chemie (CUR)
3D
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
4E
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5F, G
(B)
3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACIDnon-polymer194.22Chemie (FER)
6H, I
(A, B)
waterwater18.0278Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight25923.2
Non-Polymers*Number of molecules5
Total formula weight841.8
All*Total formula weight26765.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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