4PM7
Crystal structure of CTX-M-14 S70G:S237A in complex with cefotaxime at 1.29 Angstroms resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase CTX-M-14 | polymer | 263 | 27954.5 | 1 | UniProt (G8XD06) Pfam (PF13354) UniProt (by SIFTS) (A0A0H3H219) | Klebsiella pneumoniae subsp. pneumoniae | |
| 2 | B (A) | (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-8-oxo-5-thia-1-azabicy clo[4.2.0]oct-2-ene-2-carboxylic acid | non-polymer | 455.5 | 1 | Chemie (CE3) PubChem (16396922) PubChem (2632) PubChem (44555) PubChem (456256) PubChem (53850835) PubChem (53850836) PubChem (53850837) PubChem (5361298) PubChem (5361354) PubChem (5479527) PubChem (5916965) PubChem (87963272) PubChem (88595673) PubChem (88595674) PubChem (6540461) PubChem (6604086) PubChem (6914272) PubChem (7566336) PubChem (9703676) PubChem (9868614) PubChem (12763159) PubChem (12971804) PubChem (5742673) PubChem (6398645) PubChem (123797533) PubChem (12763160) PubChem (131711503) | |||
| 3 | C (A) | water | water | 18.0 | 413 | Chemie (HOH) |
Sequence modifications
A: 25 - 290 (UniProt: G8XD06)
| PDB | External Database | Details |
|---|---|---|
| Gly 70 | Ser 73 | engineered mutation |
| Ala 237 | Ser 240 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27954.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 455.5 | |
| All* | Total formula weight | 28410.0 |
