4PM7
Crystal structure of CTX-M-14 S70G:S237A in complex with cefotaxime at 1.29 Angstroms resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase CTX-M-14 | polymer | 263 | 27954.5 | 1 | UniProt (G8XD06) Pfam (PF00144) Pfam (PF13354) UniProt (by SIFTS) (A0A0H3H219) | Klebsiella pneumoniae subsp. pneumoniae | |
| 2 | B (A) | (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-8-oxo-5-thia-1-azabicy clo[4.2.0]oct-2-ene-2-carboxylic acid | non-polymer | 455.5 | 1 | Chemie (CE3) | |||
| 3 | C (A) | water | water | 18.0 | 413 | Chemie (HOH) |
Sequence modifications
A: 25 - 290 (UniProt: G8XD06)
| PDB | External Database | Details |
|---|---|---|
| Gly 70 | Ser 73 | engineered mutation |
| Ala 237 | Ser 240 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27954.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 455.5 | |
| All* | Total formula weight | 28410.0 |
