4PLA

Crystal structure of phosphatidyl inositol 4-kinase II alpha in complex with ATP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Chimera protein of Phosphatidylinositol 4-kinase type 2-alpha and Lysozyme	polymer	556	63240.9	1	UniProt (Q9BTU6) UniProt (D9IEF7) Pfam (PF00454) Pfam (PF00959) In PDB	Homo sapiens (Human)	Phosphatidylinositol 4-kinase type II-alpha
2	A	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
3		water	water		18.0	1	Chemie (HOH)

Sequence modifications

A: 76 - 172 (UniProt: Q9BTU6)

PDB	External Database	Details
Gly 72	-	expression tag
Ala 73	-	expression tag
Met 74	-	expression tag
Gly 75	-	expression tag

A: 1004 - 1166 (UniProt: D9IEF7)

PDB	External Database	Details
Thr 1056	Cys 54	engineered mutation
Ala 1099	Cys 97	engineered mutation

A: 180 - 468 (UniProt: Q9BTU6)

PDB	External Database	Details
Gly 1001	-	linker
Thr 1002	-	linker
Gly 1003	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	63240.9
Non-Polymers*	Number of molecules	2
	Total formula weight	1014.4
All*	Total formula weight	64255.3

*Water molecules are not included.