4PJE
Structure of human MR1-Ac-6-FP in complex with human MAIT B-B10 TCR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Major histocompatibility complex class I-related gene protein | polymer | 271 | 31711.7 | 2 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | MHC class I-related gene protein,Class I histocompatibility antigen-like protein |
| 2 | B, D (B, D) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | E, G (E, G) | TCR-alpha | polymer | 205 | 22879.4 | 2 | Homo sapiens (Human) | ||
| 4 | F, H (F, H) | TCR-beta | polymer | 245 | 27642.7 | 2 | Homo sapiens (Human) | ||
| 5 | I, Q, U (A, C, F) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 6 | J, K, O, P, S... (A, B, D, F, H) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 7 | L, M, T (A, E) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 8 | N, R (A, C) | N-(6-formyl-4-oxo-3,4-dihydropteridin-2-yl)acetamide | non-polymer | 233.2 | 2 | Chemie (30W) | |||
| 9 | V, Y (F, H) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 10 | AA, BA, CA, DA, EA... (A, B, C, D, E...) | water | water | 18.0 | 1463 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 270 (UniProt: Q95460)
B, D: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 261 | Cys 283 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 188226.2 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 1532.6 | |
| All* | Total formula weight | 189758.8 |
