4PJD
Structure of human MR1-5-OP-RU in complex with human MAIT C-C10 TCR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Major histocompatibility complex class I-related gene protein | polymer | 271 | 31711.7 | 2 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) In PDB | Homo sapiens (Human) | MHC class I-related gene protein,Class I histocompatibility antigen-like protein |
2 | B, D | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
3 | E, G | TCR-alpha | polymer | 205 | 22889.4 | 2 | Homo sapiens (Human) | ||
4 | F, H | TCR-beta | polymer | 245 | 27569.6 | 2 | Homo sapiens (Human) | ||
5 | A, C | 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol | non-polymer | 316.3 | 2 | Chemie (2LJ) | |||
6 | E | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
7 | water | water | 18.0 | 630 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 270 (UniProt: Q95460)
B, D: 1 - 99 (UniProt: P61769)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Ser 261 | Cys 283 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 188100.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 724.7 | |
All* | Total formula weight | 188824.7 |