4PJ7
Structure of human MR1-5-OP-RU in complex with human MAIT TRBV6-4 TCR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Major histocompatibility complex class I-related gene protein | polymer | 271 | 31711.7 | 2 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | MHC class I-related gene protein,Class I histocompatibility antigen-like protein |
| 2 | B, D (B, D) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | E, G (E, G) | TCR-alpha | polymer | 203 | 22652.1 | 2 | Homo sapiens (Human) | ||
| 4 | F, H (F, H) | TCR-beta | polymer | 243 | 27036.1 | 2 | Homo sapiens (Human) | ||
| 5 | I, J (A, C) | 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol | non-polymer | 316.3 | 2 | Chemie (2LJ) | |||
| 6 | K, L, M, N, O... (A, B, C, D, E...) | water | water | 18.0 | 528 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 270 (UniProt: Q95460)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 261 | Cys 283 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 186296.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 632.6 | |
| All* | Total formula weight | 186928.7 |
