4PIS

Crystal structure of human adenovirus 8 protease in complex with a nitrile inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protease	polymer	204	22993.3	1	UniProt (B9A5C1) Pfam (PF00770) In PDB	Human adenovirus 8 (HAdV-8)
2	B	PVI	polymer	11	1370.7	1	UniProt (B9A5B9) In PDB	Human adenovirus 8
3	A	N~2~-[(2R)-2-(3,5-dichlorophenyl)-2-(dimethylamino)acetyl]-N-({2-[(Z)-iminomethyl]pyrimidin-4-yl}methyl)-L-isoleucinamide	non-polymer		479.4	1	Chemie (3FU)
4		water	water		18.0	32	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	24364.0
Non-Polymers*	Number of molecules	1
	Total formula weight	479.4
All*	Total formula weight	24843.4

*Water molecules are not included.