4PIR
X-ray structure of the mouse serotonin 5-HT3 receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | 5-hydroxytryptamine receptor 3A | polymer | 456 | 52609.7 | 5 | UniProt (P23979) Pfam (PF02931) Pfam (PF02932) | Mus musculus (Mouse) | 5-HT3A,5-hydroxytryptamine receptor 3,5-HT3R,Serotonin receptor 3A,Serotonin-gated ion channel receptor |
| 2 | F, G, H, I, J (F, G, H, I, J) | VHH15 | polymer | 124 | 13458.9 | 5 | Lama glama | ||
| 3 | K, M, O, P, R... (K, M, O, P, R...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 4 | L, N, Q, T, W (L, N, Q, T, W) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 5 | In PDB GlyTouCan (G15407YE) | |||
| 5 | AA, CA, FA, Y, Z (C, D, E, A, B) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 6 | BA, GA, HA (D, H) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | DA, EA (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A, B, C, D, E: 1 - 462 (UniProt: P23979)
| PDB | External Database | Details |
|---|---|---|
| Ala 4 | Glu 31 | conflict |
| Arg 5 | - | insertion |
| Ala 277 | - | insertion |
| Ser 461 | Tyr 480 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 330342.8 | |
| Branched | Number of molecules | 14 |
| Total formula weight | 6752.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 907.9 | |
| All* | Total formula weight | 338003.0 |
