4PIN
Ergothioneine-biosynthetic methyltransferase EgtD in complex with N,N-dimethylhistidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histidine-specific methyltransferase EgtD | polymer | 323 | 35282.7 | 2 | UniProt (A0R5M8) Pfam (PF10017) | Mycobacterium smegmatis | Histidine-alpha-N-methyltransferase |
| 2 | C, G (A, B) | N,N-dimethyl-L-histidine | non-polymer | 183.2 | 2 | Chemie (AVI) | |||
| 3 | D, E, F, H, I (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 5 | Chemie (PO4) | |||
| 4 | J, K (A, B) | water | water | 18.0 | 680 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 321 (UniProt: A0R5M8)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 2 | Thr 2 | engineered mutation |
| Thr 29 | Ala 29 | engineered mutation |
| Gln 30 | Pro 30 | engineered mutation |
| Ser 75 | Ala 75 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70565.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 841.3 | |
| All* | Total formula weight | 71406.7 |
