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4PHA

Structure of human DNA polymerase beta complexed with A in the template base paired with incoming non-hydrolyzable CTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer32937536.81UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)
2B
(T)
DNA (5'-D(*CP*CP*GP*AP*CP*AP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer164828.11synthetic construct
3C
(P)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3')polymer103085.01synthetic construct
4D
(D)
DNA (5'-D(P*GP*TP*CP*GP*G)-3')polymer51536.01synthetic construct
5E, F
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6G, H
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
7I
(A)
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidinenon-polymer466.21Chemie (0KX)
8J, K, L, M
(A, T, P, D)
waterwater18.074Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight46986.0
Non-Polymers*Number of molecules5
Total formula weight560.8
All*Total formula weight47546.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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