4PG8
Crystal structure of S. aureus Homoserine Dehydrogenase at pH8.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Homoserine dehydrogenase | polymer | 468 | 51384.2 | 2 | UniProt (N6FDB4) Pfam (PF03447) Pfam (PF00742) Pfam (PF22101) UniProt (by SIFTS) (A0A0M3KKV6) | Staphylococcus aureus M1064 | HDH |
| 2 | C, D, E, F, G... (A, B) | ACETATE ION | non-polymer | 59.0 | 16 | Chemie (ACT) | |||
| 3 | L, U, V (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 4 | T (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | W (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | X, Y (A, B) | water | water | 18.0 | 302 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 426 (UniProt: N6FDB4)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Leu 427 | - | expression tag |
| Glu 428 | - | expression tag |
| Asp 429 | - | expression tag |
| Pro 430 | - | expression tag |
| Ala 431 | - | expression tag |
| Ala 432 | - | expression tag |
| Asn 433 | - | expression tag |
| Lys 434 | - | expression tag |
| Ala 435 | - | expression tag |
| Arg 436 | - | expression tag |
| Lys 437 | - | expression tag |
| Glu 438 | - | expression tag |
| Ala 439 | - | expression tag |
| Glu 440 | - | expression tag |
| Leu 441 | - | expression tag |
| Ala 442 | - | expression tag |
| Ala 443 | - | expression tag |
| Ala 444 | - | expression tag |
| Thr 445 | - | expression tag |
| Ala 446 | - | expression tag |
| Glu 447 | - | expression tag |
| Gln 448 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 102768.4 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 1433.3 | |
| All* | Total formula weight | 104201.7 |
