4PAQ
A conserved phenylalanine as relay between the 5 helix and the GDP binding region of heterotrimeric G protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40415.0 | 1 | UniProt (P10824) Pfam (PF00503) | Rattus norvegicus (Rat) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (A) | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (GSP) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence modifications
A: 1 - 354 (UniProt: P10824)
| PDB | External Database | Details |
|---|---|---|
| Tyr 336 | Phe 336 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40415.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 563.6 | |
| All* | Total formula weight | 40978.6 |
