4P8X
The crystal structures of YKL-39 in the presence of chitooligosaccharides (GlcNAc6) were solved to resolutions of 2.48 angstrom
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Chitinase-3-like protein 2 | polymer | 371 | 41619.2 | 1 | UniProt (Q15782) Pfam (PF00704) | Homo sapiens (Human) | Chondrocyte protein 39,YKL-39 |
| 2 | B (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1237.2 | 1 | In PDB GlyTouCan (G36414FS) | |||
| 3 | C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | F (A) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
A: 27 - 390 (UniProt: Q15782)
| PDB | External Database | Details |
|---|---|---|
| Ala 20 | - | expression tag |
| Met 21 | - | expression tag |
| Ala 22 | - | expression tag |
| Asp 23 | - | expression tag |
| Ile 24 | - | expression tag |
| Gly 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Val 182 | Ala 182 | engineered mutation |
| Trp 318 | Arg 318 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41619.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1237.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 43144.6 |
