4P8Q
Crystal Structure of Human Insulin Regulated Aminopeptidase with Alanine in Active Site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Leucyl-cystinyl aminopeptidase | polymer | 872 | 100227.0 | 2 | UniProt (Q9UIQ6) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) In PDB | Homo sapiens (Human) | Cystinyl aminopeptidase,Insulin-regulated membrane aminopeptidase,Insulin-responsive aminopeptidase,IRAP,Oxytocinase,OTase,Placental leucine aminopeptidase,P-LAP |
| 2 | C, D, E, F, G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 11 | Chemie (NAG) | |||
| 5 | A, B | UNKNOWN LIGAND | non-polymer | 2 | Chemie (UNL) | ||||
| 6 | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A, B: 155 - 1025 (UniProt: Q9UIQ6)
| PDB | External Database | Details |
|---|---|---|
| Ser 154 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 200454.0 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2122.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2564.1 | |
| All* | Total formula weight | 205140.1 |
