4P7U
Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with NDSB-201
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TGF-beta receptor type-2 | polymer | 112 | 12755.4 | 1 | UniProt (P37173) Pfam (PF08917) | Homo sapiens (Human) | TGFR-2,TGF-beta type II receptor,Transforming growth factor-beta receptor type II,TbetaR-II |
| 2 | B (A) | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE | non-polymer | 201.2 | 1 | Chemie (1PS) | |||
| 3 | C (A) | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence modifications
A: 27 - 136 (UniProt: P37173)
| PDB | External Database | Details |
|---|---|---|
| Met 25 | - | initiating methionine |
| Ala 26 | - | engineered mutation |
| Thr 97 | Lys 145 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12755.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 201.2 | |
| All* | Total formula weight | 12956.7 |
