4P6G
Crystal Structure of Human Cathepsin S Bound to a Non-covalent Inhibitor.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Cathepsin S | polymer | 226 | 25135.1 | 4 | UniProt (P25774) Pfam (PF00112) In PDB | Homo sapiens (Human) | |
2 | A, B, C, D | (3R,4S)-4-[(4-fluorobenzoyl)amino]-6-[4-(oxetan-3-yl)piperazin-1-yl]-3,4-dihydro-2H-chromen-3-yl methylcarbamate | non-polymer | 484.5 | 4 | Chemie (2FZ) | |||
3 | water | water | 18.0 | 894 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 0 - 217 (UniProt: P25774)
PDB | External Database | Details |
---|---|---|
Glu 218 | - | expression tag |
Gly 219 | - | expression tag |
His 220 | - | expression tag |
His 221 | - | expression tag |
His 222 | - | expression tag |
His 223 | - | expression tag |
His 224 | - | expression tag |
His 225 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 100540.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1938.1 | |
All* | Total formula weight | 102478.6 |