4P62
Directed evolution of a B3 metallo-beta-lactamase AIM-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Metallo-beta-lactamase AIM-1 | polymer | 295 | 31146.1 | 1 | UniProt (B5DCA0) | Pseudomonas aeruginosa | |
| 2 | B, C, D (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | F (A) | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A: 1 - 294 (UniProt: B5DCA0)
| PDB | External Database | Details |
|---|---|---|
| Gln 44 | Leu 44 | engineered mutation |
| Leu 102 | Phe 102 | engineered mutation |
| Tyr 216 | Phe 216 | engineered mutation |
| Ala 295 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31146.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 258.3 | |
| All* | Total formula weight | 31404.4 |
