4P5W

Structure of the N- and C-terminal domain fusion of the human mitochondrial aspartate/glutamate carrier Citrin in the calcium-bound state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Calcium-binding mitochondrial carrier protein Aralar2,Calcium-binding mitochondrial carrier protein Aralar2	polymer	411	45980.1	2	UniProt (Q9UJS0) Pfam (PF00153) In PDB	Homo sapiens (Human)	Citrin, Mitochondrial aspartate glutamate carrier 2, Solute carrier family 25 member 13,Citrin, Mitochondrial aspartate glutamate carrier 2, Solute carrier family 25 member 13
2	A, B	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3		water	water		18.0	148	Chemie (HOH)

Sequence modifications

A, B: 2 - 605 (UniProt: Q9UJS0)

PDB	External Database	Details
Met -21	-	expression tag
Ser -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Asp -10	-	expression tag
Arg -9	-	expression tag
Ala -8	-	expression tag
Ile -7	-	expression tag
Glu -6	-	expression tag
Gly -5	-	expression tag
Arg -4	-	expression tag
Thr -3	-	expression tag
Ala -2	-	expression tag
Thr -1	-	expression tag
Ser 0	-	expression tag
Glu 1	-	expression tag

A, B: 612 - 675 (UniProt: Q9UJS0)

PDB	External Database	Details
Asn 607	-	linker
Leu 608	-	linker
Tyr 609	-	linker
Phe 610	-	linker
Gln 611	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	91960.2
Non-Polymers*	Number of molecules	2
	Total formula weight	80.2
All*	Total formula weight	92040.3

*Water molecules are not included.