4P5W

Structure of the N- and C-terminal domain fusion of the human mitochondrial aspartate/glutamate carrier Citrin in the calcium-bound state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Calcium-binding mitochondrial carrier protein Aralar2,Calcium-binding mitochondrial carrier protein Aralar2	polymer	411	45980.1	2	UniProt (Q9UJS0) Pfam (PF00153)	Homo sapiens (Human)	Citrin, Mitochondrial aspartate glutamate carrier 2, Solute carrier family 25 member 13,Citrin, Mitochondrial aspartate glutamate carrier 2, Solute carrier family 25 member 13
2	C, D (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3	E, F (A, B)	water	water		18.0	148	Chemie (HOH)

Sequence modifications

A, B: 2 - 605 (UniProt: Q9UJS0)

PDB	External Database	Details
Met -21	-	expression tag
Ser -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Asp -10	-	expression tag
Arg -9	-	expression tag
Ala -8	-	expression tag
Ile -7	-	expression tag
Glu -6	-	expression tag
Gly -5	-	expression tag
Arg -4	-	expression tag
Thr -3	-	expression tag
Ala -2	-	expression tag
Thr -1	-	expression tag
Ser 0	-	expression tag
Glu 1	-	expression tag

A, B: 612 - 675 (UniProt: Q9UJS0)

PDB	External Database	Details
Asn 607	-	linker
Leu 608	-	linker
Tyr 609	-	linker
Phe 610	-	linker
Gln 611	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	91960.2
Non-Polymers*	Number of molecules	2
	Total formula weight	80.2
All*	Total formula weight	92040.3

*Water molecules are not included.