4P58
Crystal structure of mouse comt bound to an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Catechol O-methyltransferase | polymer | 212 | 23834.4 | 1 | UniProt (O88587) Pfam (PF01596) | Mus musculus (Mouse) | |
| 2 | B (A) | 1',3'-dimethyl-1H,1'H-3,4'-bipyrazole | non-polymer | 162.2 | 1 | Chemie (2F6) | |||
| 3 | C (A) | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A: 47 - 258 (UniProt: O88587)
| PDB | External Database | Details |
|---|---|---|
| Tyr 55 | His 55 | conflict |
| Asn 59 | His 59 | conflict |
| Ser 101 | Arg 101 | conflict |
| Gln 124 | Pro 124 | conflict |
| Asn 147 | Asp 147 | conflict |
| Thr 156 | Ser 156 | conflict |
| Ile 254 | Val 254 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23834.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 162.2 | |
| All* | Total formula weight | 23996.5 |
