4P4C
Human EphA3 Kinase domain in complex with quinoxaline derivatives
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | EPH receptor A3 | polymer | 361 | 40458.2 | 1 | UniProt (Q6P4R6) Pfam (PF07714) Pfam (PF07647) UniProt (by SIFTS) (P29320) In PDB | Homo sapiens (Human) | |
2 | A | 2-amino-1-(3-methoxyphenyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide | non-polymer | 333.3 | 1 | Chemie (25Q) | |||
3 | water | water | 18.0 | 274 | Chemie (HOH) |
Sequence modifications
A: 606 - 947 (UniProt: Q6P4R6)
PDB | External Database | Details |
---|---|---|
Met 587 | - | expression tag |
Gly 588 | - | expression tag |
Ser 589 | - | expression tag |
Ser 590 | - | expression tag |
His 591 | - | expression tag |
His 592 | - | expression tag |
His 593 | - | expression tag |
His 594 | - | expression tag |
His 595 | - | expression tag |
His 596 | - | expression tag |
Ser 597 | - | expression tag |
Ser 598 | - | expression tag |
Gly 599 | - | expression tag |
Leu 600 | - | expression tag |
Val 601 | - | expression tag |
Pro 602 | - | expression tag |
Arg 603 | - | expression tag |
Gly 604 | - | expression tag |
Ser 605 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40458.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 333.3 | |
All* | Total formula weight | 40791.5 |