4P3H
Crystal structure of Kaposi's sarcoma-associated herpesvirus (KSHV) protease in complex with dimer disruptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | KSHV protease | polymer | 193 | 21193.1 | 2 | UniProt (O36607) Pfam (PF00716) UniProt (by SIFTS) (Q2HRB6) | Human herpesvirus 8 (HHV-8) | |
| 2 | C, G, H (A, B) | N-[2-benzyl-4-(1H-tetrazol-5-yl)phenyl]-6-(cyclohexylmethyl)pyridine-2-carboxamide | non-polymer | 452.6 | 3 | Chemie (25G) | |||
| 3 | D (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E, F (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 314 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42386.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1606.0 | |
| All* | Total formula weight | 43992.2 |
