4P2X

Swapped Dimer of Mycobacterial Adenylyl cyclase Rv1625c: Form 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Adenylate cyclase	polymer	257	28614.2	2	UniProt (P0A4Y0) Pfam (PF00211) UniProt (by SIFTS) (P9WQ35) In PDB	Mycobacterium tuberculosis	ATP pyrophosphate-lyase,Adenylyl cyclase
2	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	A, B	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	4	Chemie (PEG)
4	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	B	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6		water	water		18.0	53	Chemie (HOH)

Sequence modifications

A, B: 212 - 443 (UniProt: P0A4Y0)

PDB	External Database	Details
Met 187	-	expression tag
Ser 188	-	expression tag
Tyr 189	-	expression tag
Tyr 190	-	expression tag
His 191	-	expression tag
His 192	-	expression tag
His 193	-	expression tag
His 194	-	expression tag
His 195	-	expression tag
His 196	-	expression tag
Asp 197	-	expression tag
Tyr 198	-	expression tag
Asp 199	-	expression tag
Ile 200	-	expression tag
Pro 201	-	expression tag
Thr 202	-	expression tag
Thr 203	-	expression tag
Glu 204	-	expression tag
Asn 205	-	expression tag
Leu 206	-	expression tag
Tyr 207	-	expression tag
Phe 208	-	expression tag
Gln 209	-	expression tag
Gly 210	-	expression tag
Ala 211	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57228.3
Non-Polymers*	Number of molecules	7
	Total formula weight	580.3
All*	Total formula weight	57808.6

*Water molecules are not included.