4P2C
Complex of Shiga toxin 2e with a neutralizing single-domain antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Shiga toxin 2e, subunit A | polymer | 297 | 33012.0 | 1 | UniProt (Q7WUF4) Pfam (PF00161) | Escherichia coli | |
| 2 | B, C, D, E, F (B, C, D, E, F) | Shiga toxin 2e, subunit B | polymer | 68 | 7590.5 | 5 | UniProt (Q47644) Pfam (PF02258) | Escherichia coli | SLT-IIeB, Shiga toxin 2 variant e B-subunit, Shiga toxin 2B subunit, Shiga toxin 2e B, Shiga toxin 2e subunit B, Shiga-like toxin 2B-subunit, Shiga-like toxin IIe variant subunit B, Slt-IIvB, Verotoxin 2e subunit B |
| 3 | G, H, I, J, K (G, H, I, J, K) | Nanobody 1, Anti-F4+ETEC bacteria VHH variable region | polymer | 128 | 14196.6 | 5 | UniProt (R9VYW2) Pfam (PF07686) | Lama glama (Llama) |
Sequence modifications
A: 1 - 297 (UniProt: Q7WUF4)
| PDB | External Database | Details |
|---|---|---|
| Ser 77 | Tyr 99 | engineered mutation |
| Gln 167 | Glu 189 | engineered mutation |
| Thr 274 | Lys 296 | variant |
| Ser 291 | Pro 313 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 141947.5 | |
| All* | Total formula weight | 141947.5 |
