4P1X
Crystal structure of staphylococcal LUK prepore
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, D, F, H | Gamma-hemolysin component C | polymer | 296 | 33816.5 | 4 | UniProt (Q99RL1) Pfam (PF07968) In PDB | Staphylococcus aureus | LukS |
2 | A, C, E, G | Gamma-hemolysin component B | polymer | 309 | 35310.1 | 4 | UniProt (Q931F3) Pfam (PF07968) UniProt (by SIFTS) (A0A0H3JX61) In PDB | Staphylococcus aureus | LukF |
3 | A, C, E, G | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 4 | Chemie (MPD) | |||
4 | water | water | 18.0 | 1057 | Chemie (HOH) |
Sequence modifications
B, D, F, H: -1 - 284 (UniProt: Q99RL1)
A, C, E, G: 2 - 300 (UniProt: Q931F3)
PDB | External Database | Details |
---|---|---|
Met -11 | - | expression tag |
Gly -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met -8 | - | expression tag |
Gly -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
Ala 0 | - | expression tag |
Met 1 | - | expression tag |
Arg 256 | Cys 281 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 276506.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 472.7 | |
All* | Total formula weight | 276979.0 |