4P1A

Thallium-bound inward-facing state of the glutamate transporter homologue GltPh

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	GltPh	polymer	422	44615.9	3	UniProt (O59010) Pfam (PF00375)	Pyrococcus horikoshii	425aa long hypothetical proton glutamate symport protein
2	D, E, G, H, J... (A, B, C)	THALLIUM (I) ION	non-polymer		204.4	6	Chemie (TL)
3	F, I, L (A, B, C)	MERCURY (II) ION	non-polymer		200.6	3	Chemie (HG)

Sequence modifications

A, B, C: 1 - 417 (UniProt: O59010)

PDB	External Database	Details
His 37	Asp 37	engineered mutation
His 40	Lys 40	engineered mutation
Cys 55	Lys 55	engineered mutation
His 125	Lys 125	engineered mutation
His 132	Lys 132	engineered mutation
His 223	Lys 223	engineered mutation
His 264	Lys 264	engineered mutation
Ala 321	Cys 321	engineered mutation
Cys 364	Ala 364	engineered mutation
His 368	Glu 368	engineered mutation
Thr 418	-	expression tag
Leu 419	-	expression tag
Val 420	-	expression tag
Pro 421	-	expression tag
Arg 422	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	133847.7
Non-Polymers*	Number of molecules	9
	Total formula weight	1828.1
All*	Total formula weight	135675.8

*Water molecules are not included.